Description

1-Isothiocyanato-4-(Methylsulfonyl)Benzene is a high-purity, synthetically valuable organic intermediate characterized by its reactive isothiocyanate and electron-withdrawing methylsulfonyl functional groups. This compound is essential for researchers and manufacturers developing advanced molecules in life sciences and material chemistry. It is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry, crop protection, and polymer synthesis.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its bioactivity for crop protection solutions.
• Chemical Biology Probe Development: Serves as a versatile reagent for creating activity-based probes (ABPs) to study enzyme function and target engagement.
• Material Science Research: Employed as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Organic Synthesis Reagent: Utilized in various organic transformations, including cycloadditions and nucleophilic addition reactions, to construct complex heterocyclic structures.

Basic Information

Product Name	1-Isothiocyanato-4-(Methylsulfonyl)Benzene
CAS No.	15863-56-6
Molecular Formula	C8H7NO2S2
Molecular Weight	213.28 g/mol
Synonyms	4-Isothiocyanato-1-(methylsulfonyl)benzene; p-(Methylsulfonyl)phenyl Isothiocyanate; 4-(Methylsulfonyl)phenyl Isothiocyanate; 1-Methylsulfonyl-4-isothiocyanatobenzene; 4-Methylsulfonylphenyl Isothiocyanate; NSC 403119; 4-(Methanesulfonyl)phenyl Isothiocyanate
EINECS	Contact for details

Quality Control

Our 1-Isothiocyanato-4-(Methylsulfonyl)Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and a Certificate of Analysis (COA) with every shipment, confirming it meets the agreed specifications for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure the container is kept tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.