Description

3-Bromo-2-Methoxy-5-Nitropyridine is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique molecular structure, featuring bromine, methoxy, and nitro substituents on a pyridine ring, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive halogen and nitro groups.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination due to the bromine substituent.
• Nucleophilic Aromatic Substitution: The nitro and methoxy groups activate the pyridine ring for selective substitution reactions, enabling diverse derivatization.
• Chemical Research & Development: A valuable tool compound in academic and industrial labs for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	3-Bromo-2-Methoxy-5-Nitropyridine
CAS No.	15862-50-7
Molecular Formula	C6H5BrN2O3
Molecular Weight	233.02 g/mol
Synonyms	5-Nitro-3-bromo-2-methoxypyridine; 2-Methoxy-3-bromo-5-nitropyridine; 3-Bromo-2-methoxy-5-nitropyridine; Pyridine, 3-bromo-2-methoxy-5-nitro-; 15862-50-7
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Methoxy-5-Nitropyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment supports applications requiring high standards, from early-stage research to scale-up under cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (HPLC)	≥98.0% / ≥99.0% (Higher Grades Available)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.