Description

3-Bromo-5-Nitropyridine is a versatile and high-purity halogenated nitropyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and nitro substituents on the pyridine ring, makes it an essential intermediate for constructing complex molecules. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive halogen and nitro groups for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive compounds, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes and protein interactions.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions, enabling the introduction of the pyridine core into more complex architectures.

Basic Information

Product Name	3-Bromo-5-Nitropyridine
CAS No.	15862-30-3
Molecular Formula	C5H3BrN2O2
Molecular Weight	202.99 g/mol
Synonyms	5-Nitro-3-bromopyridine; 3-Bromo-5-nitropyridine; 3-Bromopyridine, 5-nitro-; Pyridine, 3-bromo-5-nitro-; 3-Br-5-NO2-Pyridine; 3-Bromo-5-nitro-pyridine; 5-Nitro-3-bromo-pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Nitropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	108 - 112 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.