Description

4-Iodophenyl Isocyanate is a versatile and highly reactive aromatic isocyanate derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to introduce both the isocyanate functional group and an iodine atom into target molecules, enabling the construction of complex chemical architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing active pharmaceutical ingredients (APIs), specialty polymers, and high-value chemical intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of urea and carbamate derivatives for potential drug candidates, including kinase inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides by forming stable urea linkages in active ingredients.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing specialized polyurethanes, polyureas, and coatings with tailored properties.
• Chemical Research & Development: A valuable reagent for constructing diverse heterocyclic compounds and for use in palladium-catalyzed cross-coupling reactions (e.g., Sonogashira, Suzuki) due to the presence of the iodine substituent.
• Ligand & Catalyst Preparation: Employed to synthesize isocyanate-functionalized ligands for metal complexes used in catalysis.
• Surface Modification: Used to functionalize surfaces (e.g., silica, polymers) with reactive isocyanate groups for further conjugation or coating applications.

Basic Information

Product Name	4-Iodophenyl Isocyanate
CAS No.	15845-62-2
Molecular Formula	C7H4INO
Molecular Weight	245.02 g/mol
Synonyms	1-Iodo-4-isocyanatobenzene; p-Iodophenyl isocyanate; Isocyanic acid, 4-iodophenyl ester; 4-Isocyanato-1-iodobenzene; (4-Iodophenyl)isocyanate; NSC 406908
EINECS	Contact for details

Quality Control

Our 4-Iodophenyl Isocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay, identity confirmation, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition. Keep away from strong bases and organic solvents.

Specification

Item	Specification
Appearance	White to pale yellow crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.