Description

4-Chloropyridine-2-Carboxylic Acid tert-Butyl Ester is a high-purity, versatile chemical intermediate essential for advanced organic synthesis. Its value lies in its protected carboxylic acid group and reactive chloropyridine core, which facilitate efficient, multi-step reactions in controlled environments. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing functionalized pyridine scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the chloropyridine moiety is a critical structural component.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials and metal-organic frameworks (MOFs) due to its potential for further functionalization.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-Chloropyridine-2-Carboxylic Acid tert-Butyl Ester
CAS No.	15583-17-2
Molecular Formula	C10H12ClNO2
Molecular Weight	213.66 g/mol
Synonyms	tert-Butyl 4-chloropyridine-2-carboxylate; 4-Chloro-2-pyridinecarboxylic acid 1,1-dimethylethyl ester; 2-Pyridinecarboxylic acid, 4-chloro-, 1,1-dimethylethyl ester; 4-Chloropicolinic acid tert-butyl ester; 4-Chloro-picolinic acid tert-butyl ester; tert-Butyl 4-chloropicolinate; 4-Chloro-2-(tert-butoxycarbonyl)pyridine
EINECS	Contact for details

Quality Control

Every batch of 4-Chloropyridine-2-Carboxylic Acid tert-Butyl Ester is produced and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure compliance with exacting purity standards suitable for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical 98-99%)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.