Description

2-Dehydro-3-Methoxy Tibolone is a key pharmaceutical intermediate and steroid derivative. This compound is of significant interest for its role in the synthesis of advanced steroid-based therapeutics, particularly in the development of selective tissue estrogenic activity regulators. It is primarily utilized by pharmaceutical R&D laboratories, API manufacturers, and fine chemical suppliers serving the global healthcare sector. Its precise chemical structure makes it a critical building block for targeted hormonal therapies.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of Tibolone and related steroid hormone analogs.
• Research & Development: Used in biochemical and pharmacological research to study steroid receptor modulation and metabolic pathways.
• Active Pharmaceutical Ingredient (API) Manufacturing: Serves as a key building block in the multi-step production of complex steroid-based APIs under GMP conditions.
• Hormone Therapy Development: Employed in the development of novel therapeutics for menopause management, osteoporosis, and other endocrine-related conditions.
• Reference Standard: Used as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical laboratories.
• Fine Chemical Synthesis: A valuable synthon for creating specialized steroid derivatives with modified biological activity.

Basic Information

Item	Detail
Product Name	2-Dehydro-3-Methoxy Tibolone
CAS No.	15506-05-5
Molecular Formula	C21H28O2
Molecular Weight	312.45 g/mol
Synonyms	7α-Methylnorethynodrel; 7α-Methyl-17α-ethynyl-17β-hydroxy-5(10)-estren-3-one; Org OD-14 Intermediate; Tibolone Impurity; Tibolone Related Compound A; (7α,17α)-17-Hydroxy-7-methyl-19-nor-17-pregn-5(10)-en-20-yn-3-one; 3-Methoxy-7α-methyl-19-nor-17α-pregna-5(10)-en-20-yn-17-ol
EINECS	Contact for details

Quality Control

Our 2-Dehydro-3-Methoxy Tibolone is produced and tested to meet the stringent requirements of pharmaceutical ingredient applications. Quality is assured through a comprehensive battery of analytical tests including HPLC, NMR, and mass spectrometry for identity confirmation and purity verification. We provide full traceability and Certificates of Analysis (COA) are available for every batch, detailing all critical parameters. Our quality system is designed to support GMP compliance for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.