Description

5-Isopropylidene-2,2,4,4-tetramethyl-1-oxaspiro[2.2]pentane is a specialized spirocyclic ether compound with a unique bridged structure, offering significant value as a high-purity intermediate and building block in advanced organic synthesis. Its rigid molecular framework makes it particularly valuable for creating complex, three-dimensional architectures in pharmaceuticals and advanced materials. This compound is essential for R&D chemists and process engineers in the fine chemical, pharmaceutical, and specialty polymer industries seeking to develop novel active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block or scaffold in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or antiviral drugs.
• Advanced Material Synthesis: Used in the development of specialty polymers, liquid crystals, or organic frameworks where its spirocyclic structure imparts specific rigidity or optical properties.
• Agrochemical Research: Acts as a precursor in the design and synthesis of new-generation herbicides or plant growth regulators with novel modes of action.
• Flavor & Fragrance Chemistry: Employed as an intermediate for creating complex, musky, or woody odorant molecules due to its unique carbon skeleton.
• Catalyst Ligand Development: Its structure can be functionalized to create novel ligands for asymmetric catalysis in industrial chemical processes.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, exploring new cyclization or rearrangement reactions.

Basic Information

Product Name	5-Isopropylidene-2,2,4,4-tetramethyl-1-oxaspiro[2.2]pentane
CAS No.	15448-69-8
Molecular Formula	C11H18O
Molecular Weight	166.26 g/mol
Synonyms	1-Oxaspiro[2.2]pentane, 5-isopropylidene-2,2,4,4-tetramethyl-; 2,2,4,4-Tetramethyl-5-isopropylidene-1-oxaspiro[2.2]pentane; Spiro[2.2]pentane, 5-isopropylidene-2,2,4,4-tetramethyl-1-oxa-; 5-(Propan-2-ylidene)-2,2,4,4-tetramethyl-1-oxaspiro[2.2]pentane
EINECS	Contact for details

Quality Control

Our 5-Isopropylidene-2,2,4,4-tetramethyl-1-oxaspiro[2.2]pentane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from GC, HPLC, and NMR analyses. For customers with specific regulatory needs, we can support documentation for cGMP, ISO, or REACH compliance upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and potential concentration changes. Recommended storage temperature is 2-8°C for long-term stability, although short-term storage at controlled room temperature (15-25°C) is acceptable.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 3.0%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.