Description

1-O,6-o-Bis(Methylsulfonyl)-D-Mannitol 2,3,4,5-Tetraacetate is a high-purity, multi-functional synthetic intermediate derived from D-mannitol. This compound is valued for its unique chemical structure, featuring both sulfonyl and acetyl protecting groups, which makes it a versatile building block for complex organic synthesis. It is primarily sought after by research institutions and pharmaceutical developers for the production of specialized carbohydrates, nucleoside analogs, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside analogs and antiviral/antitumor agents.
• Carbohydrate Chemistry: Used as a protected mannitol derivative for constructing complex oligosaccharides and glycoconjugates.
• Chemical Research: Serves as a versatile building block in organic synthesis for introducing specific functional groups.
• Process Development: Employed in scaling up routes for specialty fine chemicals and active pharmaceutical ingredients (APIs).
• Bioconjugation: Potential use in linker chemistry for drug-antibody conjugates (ADCs) due to its reactive sulfonyl groups.

Basic Information

Product Name	1-O,6-o-Bis(Methylsulfonyl)-D-Mannitol 2,3,4,5-Tetraacetate
CAS No.	15410-48-7
Molecular Formula	C16H26O14S2
Molecular Weight	506.50 g/mol
Synonyms	D-Mannitol, 1,6-bis(methylsulfonyl)-, 2,3,4,5-tetraacetate; 1,6-Di-O-methylsulfonyl-2,3,4,5-tetra-O-acetyl-D-mannitol; 1,6-Bis-O-(methylsulfonyl)-2,3,4,5-tetra-O-acetyl-D-mannitol; Tetraacetyl-1,6-dimethanesulfonyl-D-mannitol; 1,6-Dimesyl-2,3,4,5-tetraacetylmannitol
EINECS	Contact for details

Quality Control

Our 1-O,6-o-Bis(Methylsulfonyl)-D-Mannitol 2,3,4,5-Tetraacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.