Description

Methyl 4-Hydroxy-3-Iodobenzoate is a high-purity iodinated aromatic ester, a key synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of the iodine and hydroxyl groups, which enable versatile functionalization for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of thyroid hormone analogs and other iodine-containing therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides, where the iodine atom facilitates further cross-coupling reactions.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating iodinated aromatic cores used in electronic display technologies and organic light-emitting diodes.
• Chemical Research & Development: Employed in organic synthesis laboratories for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions due to its reactive aryl iodide moiety.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized iodinated dyes and colorants with unique optical properties.
• Polymer Modification: Utilized to introduce functional aromatic groups into polymer chains, modifying thermal and mechanical properties for high-performance materials.

Basic Information

Product Name	Methyl 4-Hydroxy-3-Iodobenzoate
CAS No.	15126-06-4
Molecular Formula	C8H7IO3
Molecular Weight	278.05 g/mol
Synonyms	3-Iodo-4-hydroxybenzoic acid methyl ester; Methyl 3-iodo-4-hydroxybenzoate; 4-Hydroxy-3-iodobenzoic acid methyl ester; Benzoic acid, 4-hydroxy-3-iodo-, methyl ester; MHIBA; Methyl 4-hydroxy-3-iodobenzoate; 15126-06-4 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our Methyl 4-Hydroxy-3-Iodobenzoate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.