Description

4,7-Dihydro Megestrol Acetate is a key pharmaceutical intermediate and synthetic derivative of the progestin megestrol acetate. This compound matters for its critical role in the research and development of advanced hormonal therapies and active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical manufacturers, R&D laboratories, and fine chemical producers engaged in the synthesis of steroidal drugs.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of progestin-based APIs and other steroidal compounds.
• Research & Development: Used in academic and industrial laboratories for pharmacological studies, metabolic pathway research, and the development of new therapeutic agents.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Process Chemistry: Employed in scaling up and optimizing synthetic routes for the commercial production of related steroid molecules.

Basic Information

Product Name	4,7-Dihydro Megestrol Acetate
CAS No.	14994-27-5
Molecular Formula	C24H32O4
Molecular Weight	384.51 g/mol
Synonyms	6-Methyl-17α-acetoxy-4,7-didehydro-6-dehydro-16-methylenepregna-4,6-diene-3,20-dione; 4,7-Didehydro-6-dehydro-16-methylenemegestrol acetate; 4,7-Dihydro derivative of Megestrol Acetate; 6-Methyl-17α-hydroxy-4,7-didehydro-6-dehydro-16-methylenepregna-4,6-diene-3,20-dione 17-acetate; 4,7-Dihydro-6-dehydro-16-methylenemegestrol acetate
EINECS	Contact for details

Quality Control

Our 4,7-Dihydro Megestrol Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.