Description

D-Tryptophan Methyl Ester Hydrochloride is a protected derivative of the essential amino acid D-tryptophan, specifically formulated as a hydrochloride salt for enhanced stability and handling. This high-purity chiral building block is critical for the synthesis of complex peptides and pharmaceutical intermediates where stereochemical integrity is paramount. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and advanced organic synthesis sectors for developing novel therapeutic agents and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of peptide-based drugs, enzyme inhibitors, and other bioactive molecules.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate the D-tryptophan residue, influencing peptide conformation and biological activity.
• Biochemical Research: Serves as a standard or reagent in metabolic studies, enzyme-substrate interaction research, and proteomics.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to construct complex molecular architectures.
• Reference Standard: Used in analytical laboratories for method development, calibration, and quality control of related pharmaceutical products.

Basic Information

Product Name	D-Tryptophan Methyl Ester Hydrochloride
CAS No.	14907-27-8
Molecular Formula	C12H15ClN2O2
Molecular Weight	254.71 g/mol
Synonyms	(R)-2-Amino-3-(1H-indol-3-yl)propanoic acid methyl ester hydrochloride; Methyl (R)-2-amino-3-(1H-indol-3-yl)propanoate hydrochloride; D-Tryptophan methyl ester HCl; (R)-Tryptophan methyl ester hydrochloride; Methyl D-tryptophanate hydrochloride; H-D-Trp-OMe.HCl; (R)-1H-Indole-3-propanoic acid, α-amino-, methyl ester, hydrochloride
EINECS	Contact for details

Quality Control

Our D-Tryptophan Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.