Description

Ethyl 6-(Bromomethyl)-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is a high-value brominated heterocyclic building block essential for advanced organic synthesis. This compound matters because it serves as a versatile precursor for constructing complex nitrogen-containing molecular frameworks, enabling the development of novel active ingredients. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of dihydropyrimidinone (DHPM) derivatives, which are a privileged scaffold in medicinal chemistry with diverse biological activities.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive bromomethyl group for structural diversification.
• Chemical Biology Probe Synthesis: Employed to create tagged or modified small molecules for studying biological pathways and target engagement.
• Material Science Precursor: Can be utilized in the synthesis of specialized polymers or organic electronic materials with tailored properties.
• Academic & Contract Research: Serves as a critical starting material for methodological development and novel compound library synthesis in academic and CRO laboratories.

Basic Information

Product Name	Ethyl 6-(Bromomethyl)-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate
CAS No.	14903-94-7
Molecular Formula	C9H11BrN2O3
Molecular Weight	275.10 g/mol
Synonyms	Ethyl 6-(bromomethyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 5-Carbethoxy-6-(bromomethyl)-1,2,3,4-tetrahydropyrimidin-2-one; 6-(Bromomethyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl ester; 5-Ethoxycarbonyl-6-(bromomethyl)-1,2,3,4-tetrahydropyrimidin-2-one; Biginelli derivative bromomethyl intermediate; DHPM bromomethyl derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Ethyl 6-(Bromomethyl)-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.