Description

2,2-Dimethyl-4-(Acetoxymethyl)-1,3-Dioxolane is a specialized acetoxy-protected acetonide derivative, a key intermediate in fine chemical synthesis. Its primary value lies in its role as a versatile protecting group for diols and polyols, enabling selective reactions in complex molecule construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors who require high-purity intermediates for sensitive synthetic pathways.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of complex drug molecules, particularly in nucleoside and carbohydrate chemistry where selective protection is required.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides that require specific stereochemistry and functional group manipulation.
• Polymer & Material Science: Serves as a monomer or modifying agent in the creation of specialty polymers with tailored degradation profiles or functional properties.
• Fine Chemical Production: Employed as a building block for fragrances, flavors, and other high-value specialty chemicals.
• Academic & R&D: A valuable reagent in laboratory-scale research for method development and exploring new synthetic routes in organic chemistry.

Basic Information

Product Name	2,2-Dimethyl-4-(Acetoxymethyl)-1,3-Dioxolane
CAS No.	14739-11-8
Molecular Formula	C8H14O4
Molecular Weight	174.19 g/mol
Synonyms	1,2-Isopropylidene-3-acetoxyglycerol; 3-Acetoxy-1,2-O-isopropylidene glycerol; 1,2-O-Isopropylidene-3-acetyl-sn-glycerol; Acetone Glycerol Acetate Ketal; (2,2-Dimethyl-1,3-dioxolan-4-yl)methyl acetate; Glycerol 1,2-acetonide 3-acetate; Acetonide of Glycerol Monoacetate
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-4-(Acetoxymethyl)-1,3-Dioxolane is manufactured under a strict quality management system. We provide material suitable for research and industrial synthesis, with typical purity grades exceeding 97% (by GC/HPLC). Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We can supply material compliant with ICH Q3A/B guidelines for residual solvents and impurities upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be kept under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.420 - 1.430
Specific Gravity (20°C)	1.080 - 1.120

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.