Description

tert-Butoxycarbonylamino-Acetic Acid Ethyl Ester is a versatile Boc-protected amino acid derivative widely used as a key synthetic intermediate. Its primary value lies in providing a protected amine group for peptide synthesis and other organic transformations, ensuring reaction selectivity and yield. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries engaged in developing novel active ingredients and complex molecules.

Application

• Peptide Synthesis: A crucial building block for the solid-phase and solution-phase synthesis of peptides, where the Boc group protects the amino functionality.
• Pharmaceutical Intermediates: Serves as a key precursor in the synthesis of various active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation: Used in the preparation of modified biomolecules and linker molecules for drug delivery systems and diagnostic agents.
• Organic Synthesis: Employed in multi-step organic syntheses to introduce the glycine moiety with a protected amine, facilitating complex molecule assembly.
• Protecting Group Chemistry: Acts as a reagent for introducing the tert-butoxycarbonyl (Boc) protecting group onto other amines in synthetic pathways.
• Research & Development: A standard reagent in medicinal chemistry and chemical biology research for exploring new therapeutic compounds.

Basic Information

Product Name	tert-Butoxycarbonylamino-Acetic Acid Ethyl Ester
CAS No.	14719-37-0
Molecular Formula	C9H17NO4
Molecular Weight	203.24 g/mol
Synonyms	Boc-Gly-OEt; N-(tert-Butoxycarbonyl)glycine ethyl ester; Ethyl N-Boc-glycinate; Glycine, N-[(1,1-dimethylethoxy)carbonyl]-, ethyl ester; Ethyl 2-[(tert-butoxycarbonyl)amino]acetate; Boc-Glycine ethyl ester; N-Boc-glycine ethyl ester; 2-[(tert-Butoxycarbonyl)amino]acetic acid ethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butoxycarbonylamino-Acetic Acid Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Approx. 78-82°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.