Description

Lauric Acid n-Hydroxy-Succinimide Ester CAS NO 14565-47-0 is a high-purity, reactive chemical intermediate designed for advanced synthesis. This compound is valued for its role as an efficient acylating agent, enabling the controlled introduction of lauric acid moieties into target molecules under mild conditions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, bioconjugation, and specialty chemical sectors for developing novel active compounds and functional materials.

Application

• Bioconjugation Reagent: For the site-specific labeling of peptides, proteins, and antibodies with lipophilic chains to modify pharmacokinetic properties.
• Pharmaceutical Intermediate: In the synthesis of prodrugs and active pharmaceutical ingredients (APIs) requiring fatty acid functionalization.
• Polymer Modification: Used to introduce hydrophobic laurate groups into polymer backbones to alter material properties like solubility and degradation rates.
• Lipid Nanoparticle (LNP) Component: As a functionalizable building block in the formulation of advanced drug delivery systems for nucleic acids.
• Crosslinking Agent: For creating amide bonds in the preparation of hydrogels, biomaterials, and dendrimers.
• Surface Functionalization: To covalently attach lauric acid chains to solid supports, nanoparticles, or sensors for creating hydrophobic surfaces.

Basic Information

Product Name	Lauric Acid n-Hydroxy-Succinimide Ester
CAS No.	14565-47-0
Molecular Formula	C16H27NO4
Molecular Weight	297.39 g/mol
Synonyms	N-Hydroxysuccinimide Laurate; Lauric Acid NHS Ester; Dodecanoic Acid N-Hydroxysuccinimide Ester; NHS-Laurate; N-Succinimidyl Dodecanoate; 2,5-Dioxopyrrolidin-1-yl dodecanoate; LA-NHS; 14565-47-0
EINECS	Contact for details

Quality Control

Our Lauric Acid n-Hydroxy-Succinimide Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at temperatures between -20°C to -10°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent hydrolysis. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.