Description

3-(4-Iodophenyl)-1-Phenyl-2-Propen-1-One is a high-purity iodinated chalcone derivative, a versatile organic building block prized for its unique structural motif. This compound is critical for advanced research and development, particularly in the synthesis of complex molecules with tailored electronic and biological properties. It is primarily sought by pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry, organic electronics, and as a key intermediate in cross-coupling reactions.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and infectious diseases.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its chalcone backbone for bioactive molecule design.
• Material Science & Organic Electronics: Acts as a building block for organic semiconductors, non-linear optical (NLO) materials, and photoactive polymers due to its conjugated system and iodine atom.
• Chemical Synthesis & Catalysis: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for constructing complex biaryl and extended π-conjugated systems.
• Academic & R&D Laboratories: Employed in fundamental research on chalcone chemistry, structure-activity relationships (SAR), and as a standard for analytical method development.
• Ligand & Complex Formation: Potential use in designing ligands for metal-organic frameworks (MOFs) or catalytic metal complexes.

Basic Information

Product Name	3-(4-Iodophenyl)-1-Phenyl-2-Propen-1-One
CAS No.	14548-42-6
Molecular Formula	C15H11IO
Molecular Weight	334.15 g/mol
Synonyms	4'-Iodochalcone; (E)-3-(4-Iodophenyl)-1-phenylprop-2-en-1-one; 1-Phenyl-3-(4-iodophenyl)-2-propen-1-one; 3-(p-Iodophenyl)-1-phenyl-2-propen-1-one; Iodochalcone; p-Iodochalcone; Chalcone, 4'-iodo-; NSC 403697
EINECS	Contact for details

Quality Control

Our 3-(4-Iodophenyl)-1-Phenyl-2-Propen-1-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a Certificate of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.