Description

Methyl 2-{[(Benzyloxy)Carbonyl]Amino}-3-Hydroxypropanoate is a protected amino acid derivative, specifically a serine analog with a Cbz-protected amine and a methyl ester. This compound is a crucial chiral building block in organic synthesis, valued for its role in constructing complex peptide structures and other bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, peptide-based drugs, and advanced chemical intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of peptide-based drugs, protease inhibitors, and other active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Serves as a protected serine residue in solid-phase and solution-phase peptide synthesis (SPPS).
• Chemical Research: Used in academic and industrial R&D for exploring new synthetic methodologies and constructing complex molecular architectures.
• Bioconjugation: Acts as a precursor for linkers and spacers in antibody-drug conjugates (ADCs) and other bioconjugation strategies.
• Agrochemical Development: Employed in the research and synthesis of novel, biologically active compounds for crop protection.
• Material Science: A potential monomer or building block for designing functional polymers and advanced materials.

Basic Information

Product Name	Methyl 2-{[(Benzyloxy)Carbonyl]Amino}-3-Hydroxypropanoate
CAS No.	14464-15-4
Molecular Formula	C12H15NO5
Molecular Weight	253.25 g/mol
Synonyms	Methyl N-Cbz-L-serinate; Methyl (2S)-2-{[(benzyloxy)carbonyl]amino}-3-hydroxypropanoate; Cbz-Ser-OMe; N-Carbobenzoxy-L-serine methyl ester; Z-Ser-OMe; (S)-Methyl 2-((((benzyloxy)carbonyl)amino)-3-hydroxypropanoate; Methyl 2-(((benzyloxy)carbonyl)amino)-3-hydroxypropanoate; L-Serine, N-[(phenylmethoxy)carbonyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-{[(Benzyloxy)Carbonyl]Amino}-3-Hydroxypropanoate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical research and synthesis. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.