Description

Diethyl Phenyl Orthoformate is a specialized orthoester compound widely used as a versatile reagent and protecting group in organic synthesis. Its primary value lies in its ability to act as a formylating agent and a precursor for heterocyclic compounds, enabling the synthesis of complex molecules. This product is essential for research and development laboratories, pharmaceutical intermediates manufacturing, and fine chemical production where precise molecular construction is required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral and antibacterial agents.
• Fine Chemical Synthesis: Used as a formylating agent and protecting group for carbonyl functionalities in multi-step organic reactions.
• Agrochemical Production: Intermediate in the manufacture of certain pesticides and herbicides requiring specific heterocyclic structures.
• Dye and Pigment Chemistry: Serves as a precursor in the synthesis of complex organic dyes and colorants.
• Academic & Industrial R&D: A valuable reagent for methodological development and the exploration of new synthetic pathways in chemistry.
• Material Science: Potential use in the synthesis of monomers or specialty polymers with tailored properties.

Basic Information

Product Name	Diethyl Phenyl Orthoformate
CAS No.	14444-77-0
Molecular Formula	C13H20O3
Molecular Weight	224.30 g/mol
Synonyms	Phenyl Orthoformic Acid Triethyl Ester; Ethyl Phenyl Orthoformate; Triethoxyphenylmethane; NSC 403697; Phenyl Orthoformate Triethyl Ester; 1,1,1-Triethoxy-1-phenylmethane; Benzene, [(triethoxy)methyl]-
EINECS	Contact for details

Quality Control

Our Diethyl Phenyl Orthoformate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation. A detailed Certificate of Analysis (COA) documenting purity, assay, and impurity profiles is provided with every shipment and is available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.480 - 1.490
Density (20°C)	1.010 - 1.030 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.