Description

Trimethylsilylmethylisocyanate is a versatile organosilicon reagent featuring a reactive isocyanate group protected by a trimethylsilylmethyl moiety. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical and advanced materials chemistry. It is essential for researchers and manufacturers in the agrochemical, pharmaceutical, and specialty polymer industries who require precise and reliable intermediates for heterocycle formation and functional group transformations.

Application

• Pharmaceutical Intermediate: A crucial reagent for the synthesis of carbamates, ureas, and heterocyclic compounds with potential biological activity.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its silicon group can influence bioavailability and stability.
• Polymer Modification: Serves as a functional monomer or cross-linking agent for introducing isocyanate functionality into silicone-based or specialty polymers.
• Peptide Chemistry: Employed in the preparation of protected amino acid derivatives and peptide conjugates.
• Material Science: Acts as a surface modifying agent or a precursor for silicon-containing coatings and adhesives.
• Chemical Research: A valuable tool in organic synthesis for constructing novel molecular architectures and exploring new reaction pathways.

Basic Information

Product Name	Trimethylsilylmethylisocyanate
CAS No.	14283-35-3
Molecular Formula	C5H11NOSi
Molecular Weight	129.23 g/mol
Synonyms	Isocyanatomethyltrimethylsilane; (Isocyanatomethyl)trimethylsilane; Trimethylsilylmethyl isocyanate; TMSM-IC; (Trimethylsilyl)methyl isocyanate; NSC 241087; Silane, (isocyanatomethyl)trimethyl-
EINECS	Contact for details

Quality Control

Our Trimethylsilylmethylisocyanate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (IR, NMR), to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its highly volatile and moisture-sensitive nature, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent hydrolysis and maintain product integrity. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.