Description

16-Hydroxyprogesterone is a key steroid hormone intermediate with significant relevance in pharmaceutical synthesis. This compound matters for its role as a crucial precursor in the production of various corticosteroid and progestogen-based active pharmaceutical ingredients (APIs). Industrial buyers in the pharmaceutical and fine chemical sectors need this high-purity intermediate to ensure the quality and efficacy of their final drug products.

Application

• Pharmaceutical Intermediate: Primary use as a key building block in the synthesis of corticosteroid drugs such as hydrocortisone and its derivatives.
• Progestogen Synthesis: Serves as a critical precursor in the manufacturing pathway for various progestogen hormones.
• Research & Development: Utilized in biochemical research for studying steroid metabolism, enzyme activity, and hormone receptor interactions.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for HPLC, GC-MS, or other chromatographic methods.
• Fine Chemical Production: Used in the multi-step synthesis of other complex steroid molecules for specialized applications.

Basic Information

Product Name	16-Hydroxyprogesterone
CAS No.	14264-44-9
Molecular Formula	C21H30O3
Molecular Weight	330.46 g/mol
Synonyms	16α-Hydroxyprogesterone; 16α-Hydroxypregn-4-ene-3,20-dione; 16α-OH-P; 16α-Hydroxy-4-pregnene-3,20-dione; Pregn-4-ene-3,20-dione, 16α-hydroxy-; 16-Hydroxy-δ4-pregnene-3,20-dione
EINECS	Contact for details

Quality Control

Our 16-Hydroxyprogesterone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets the stringent requirements for pharmaceutical intermediates. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.