Description

Hexanoic Acid Trimethylsilyl Ester is a versatile organosilicon reagent primarily used as a silylating agent and a protected intermediate in organic synthesis. Its high volatility and reactivity make it a valuable tool for introducing the trimethylsilyl (TMS) group, enhancing the volatility and stability of target molecules for analytical and synthetic purposes. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly in gas chromatography derivatization and the synthesis of complex organic molecules.

Application

• Gas Chromatography (GC) Derivatization: Used to silylate polar functional groups (e.g., -OH, -COOH) in analytes to improve their volatility, thermal stability, and chromatographic performance.
• Pharmaceutical Intermediate: Serves as a key protected intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs) and other bioactive compounds.
• Agrochemical Synthesis: Employed in the production of advanced pesticides, herbicides, and plant growth regulators where silylation is a critical step.
• Polymer & Material Science: Acts as a modifying agent or monomer precursor in the development of specialty silicones and advanced polymeric materials.
• Organic Synthesis Reagent: Functions as a versatile silylating agent to protect reactive sites during complex chemical transformations.
• Analytical Reference Standard: Used as a high-purity standard in analytical laboratories for method development and quality control.

Basic Information

Product Name	Hexanoic Acid Trimethylsilyl Ester
CAS No.	14246-15-2
Molecular Formula	C9H20O2Si
Molecular Weight	188.34 g/mol
Synonyms	Caproic Acid Trimethylsilyl Ester; Trimethylsilyl Hexanoate; n-Hexanoic Acid Trimethylsilyl Ester; TMS Hexanoate; Hexanoic Acid, Trimethylsilyl Ester; Trimethylsilyl Caproate; (Trimethylsilyl)oxy]hexanal (tautomer); 1-(Trimethylsiloxy)hexan-1-one
EINECS	Contact for details

Quality Control

Our Hexanoic Acid Trimethylsilyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, keep containers tightly sealed when not in use and away from open flames, heat sources, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Density (at 20°C)	~0.86 g/mL
Refractive Index (n20D)	~1.415

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.