Description

3β,4α-Bis(Benzyloxy)-5β-(Benzyloxymethyl)Tetrahydrofuran-2-One is a high-purity, protected sugar derivative and a key chiral intermediate in organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of nucleoside analogs and other bioactive molecules. It is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries where precise stereochemistry and functional group manipulation are critical.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Chiral Synthesis: Serves as a versatile chiral template or starting material for the asymmetric synthesis of complex natural products and active pharmaceutical ingredients (APIs).
• Glycochemistry Research: Used in the study and development of modified sugars, glycosidase inhibitors, and carbohydrate-based drugs.
• Agrochemical Development: Employed as an intermediate in creating advanced, stereochemically-defined active ingredients for crop protection.
• Fine Chemical Production: Applied in the custom synthesis of specialty chemicals requiring specific protected sugar motifs.

Basic Information

Product Name	3β,4α-Bis(Benzyloxy)-5β-(Benzyloxymethyl)Tetrahydrofuran-2-One
CAS No.	14233-64-8
Molecular Formula	C26H26O5
Molecular Weight	418.48 g/mol
Synonyms	1,2-O-Dibenzyl-3-O-benzyloxymethyl-D-erythro-pentofuranos-1,4-lactone; 3,4-Di-O-benzyl-5-O-benzyloxymethyl-2,5-dihydrofuran-2-one; 3,4-Di-O-benzyl-5-O-(benzyloxymethyl)-2(5H)-furanone; Protected D-Ribonolactone derivative; Tribenzyl D-ribonolactone; 1,4-Lactone of 1,2-di-O-benzyl-3-O-benzyloxymethyl-D-erythro-pentofuranose
EINECS	Contact for details

Quality Control

Our 3β,4α-Bis(Benzyloxy)-5β-(Benzyloxymethyl)Tetrahydrofuran-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.