Description

Cyclobutanecarboxylic Acid, 2-Methyl-, Methyl Ester (8Ci,9Ci) is a specialized organic ester building block characterized by its strained cyclobutane ring system. This compound matters as a versatile chiral synthon and intermediate for advanced pharmaceutical and agrochemical research, enabling the synthesis of complex molecules with specific stereochemistry. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring a substituted cyclobutane core for conformational rigidity.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, and insecticides where the cyclobutane structure contributes to biological activity and environmental profile.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, fragrances, and advanced polymers requiring specific, high-purity organic intermediates.
• Material Science Research: Serves as a monomer or precursor for developing novel polymeric materials with unique thermal or mechanical properties derived from the strained ring.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis, including studies on ring-opening reactions, asymmetric catalysis, and stereoselective transformations.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 2-Methyl-, Methyl Ester (8Ci,9Ci)
CAS No.	14132-44-6
Molecular Formula	C7H12O2
Molecular Weight	128.17 g/mol
Synonyms	Methyl 2-methylcyclobutanecarboxylate; 2-Methylcyclobutanecarboxylic acid methyl ester; Methyl 2-methyl-1-cyclobutanecarboxylate; 1-Cyclobutanecarboxylic acid, 2-methyl-, methyl ester; NSC 163082; Methyl 2-methylcyclobutane-1-carboxylate; (1R,2S)-rel-Methyl 2-methylcyclobutanecarboxylate (for stereoisomer)
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxylic Acid, 2-Methyl-, Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.