Description

1,3-Diazaspiro[4.4]Nonane-2,4-Dione,2-Thio-(8Ci) is a specialized spirocyclic thiouracil derivative, a high-value heterocyclic building block prized for its unique constrained molecular architecture. This compound matters as a critical intermediate in advanced organic synthesis, enabling the development of novel compounds with targeted biological and material properties. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for creating new active ingredients and functional molecules.

Application

This versatile spirocyclic intermediate serves as a key precursor in several high-value synthetic pathways:

• Pharmaceutical Intermediate: Core scaffold for the research and development of novel drug candidates, particularly in areas targeting central nervous system (CNS) disorders and enzyme inhibition.
• Agrochemical Synthesis: Building block for creating new generations of herbicides, fungicides, and plant growth regulators with enhanced efficacy and selectivity.
• Material Science Research: Precursor for synthesizing specialized organic ligands, polymers, and advanced materials with unique electronic or structural properties.
• Chemical Biology & Proteomics: Used in the design and synthesis of molecular probes, activity-based probes (ABPs), and other tools for studying biological systems.
• Academic & Contract Research: Essential for methodological development in organic chemistry and for exploring new chemical spaces in both academic and industrial R&D settings.

Basic Information

Product Name	1,3-Diazaspiro[4.4]Nonane-2,4-Dione,2-Thio-(8Ci)
CAS No.	14109-98-9
Molecular Formula	C7H8N2O2S
Molecular Weight	184.22 g/mol
Synonyms	2-Thioxo-1,3-diazaspiro[4.4]nonane-4-one; 2-Thio-1,3-diazaspiro[4.4]nonane-2,4-dione; Spiro[cyclopentane-1,5'-[4,7]methano[2H,3H]imidazo[4,5-d]pyrimidine]-2',4',6',8'(1'H,3'H,5'H,7'H)-tetrone, 2'-thioxo-; 2-Thiospirohydantoin; Thiospirohydantoin derivative; 1,3-Diazaspiro[4.4]nonane-2,4-dithione (tautomer); 8CI Index Name derivative
EINECS	Contact for details

Quality Control

Our 1,3-Diazaspiro[4.4]Nonane-2,4-Dione,2-Thio-(8Ci) is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the exacting standards required for research and process development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound may be light-sensitive and/or moisture-sensitive; prolonged exposure to light, heat, or humidity should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.