Description

18-Methylethynyl Estradiol is a synthetic steroidal estrogen derivative, recognized for its potent biological activity. This high-purity compound is critical for pharmaceutical research and development, particularly in the study of hormone-related pathways and therapeutic applications. It is primarily utilized by research institutions and pharmaceutical companies engaged in endocrinology, oncology, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of steroidal drugs and hormone therapies.
• Biochemical Research: Used as a reference standard and active compound in studies of estrogen receptor binding and signaling mechanisms.
• Endocrinology Studies: Applied in vitro and in vivo research to investigate the effects of estrogen analogs on physiological systems.
• Academic Research: Utilized in university and institutional labs for fundamental research in steroid chemistry and molecular biology.
• Drug Discovery: A valuable building block in medicinal chemistry programs aimed at discovering new selective estrogen receptor modulators (SERMs).

Basic Information

Product Name	18-Methylethynyl Estradiol
CAS No.	14012-72-7
Molecular Formula	C21H26O2
Molecular Weight	310.43 g/mol
Synonyms	17α-Ethynyl-18-methylestra-1,3,5(10)-triene-3,17β-diol; 18-Methyl-17α-ethynylestradiol; 18-Methyl Ethynylestradiol; 18-ME-EE2; NSC 10973; 18-Methyl-19-nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17β-diol
EINECS	Contact for details

Quality Control

Our 18-Methylethynyl Estradiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.