Description

1-Azido-2,3,4,6-Tetra-o-Acetyl-β-D-Glucose is a key protected glycosyl donor and versatile intermediate in carbohydrate chemistry. Its value lies in providing a reactive azido group and acetyl protecting groups, enabling precise synthesis of complex oligosaccharides and glycoconjugates. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for creating nucleoside analogs, glycomimetics, and bioconjugates.

Application

• Glycosylation Reactions: A crucial building block for the stereoselective synthesis of 1,2-cis and 1,2-trans glycosidic linkages in oligosaccharide assembly.
• Nucleoside Analog Synthesis: Serves as a precursor for modified sugar moieties in antiviral and anticancer nucleoside drug candidates.
• Glycoconjugate Preparation: Used in the development of neoglycoproteins, glycolipids, and other biologically active conjugates for immunological studies.
• Chemical Biology Probes: The azido group enables bioorthogonal "click chemistry" (e.g., CuAAC, SPAAC) for labeling and imaging applications.
• Polymer & Material Science: Acts as a monomer or functionalization agent for creating carbohydrate-based polymers and smart materials.
• Library Synthesis: A valuable starting material for generating diverse sugar-based compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	1-Azido-2,3,4,6-Tetra-o-Acetyl-β-D-Glucose
CAS No.	13992-25-1
Molecular Formula	C14H19N3O9
Molecular Weight	373.32 g/mol
Synonyms	2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl azide; β-D-Glucopyranosyl azide, 2,3,4,6-tetraacetate; 1-Azido-1-deoxy-2,3,4,6-tetra-O-acetyl-β-D-glucopyranose; Tetra-O-acetyl-β-D-glucopyranosyl azide; Azido tetraacetyl glucoside; Glucosyl azide tetraacetate; β-D-Glucopyranosyl azide tetraacetate
EINECS	Contact for details

Quality Control

Our 1-Azido-2,3,4,6-Tetra-o-Acetyl-β-D-Glucose is produced under strict quality management protocols. Each batch is characterized and tested to ensure high chemical purity and structural integrity, meeting the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC/NMR), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.