Description

1,2-Cyclohexanedicarboxylic Acid, 4-Oxo-, 1,2-Dimethyl Ester, (1R,2R)-Rel- is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a key building block in the production of complex, optically active molecules, offering precise stereochemical control. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• As a critical chiral synthon in the asymmetric synthesis of pharmaceutical intermediates.
• Building block for complex natural products and bioactive molecules requiring the (1R,2R) stereochemistry.
• Intermediate in the research and development of novel catalysts and ligands for stereoselective reactions.
• Starting material for the synthesis of advanced polymers and specialty materials with specific optical properties.
• Used in process chemistry for scaling up the production of target molecules in a GMP environment.

Basic Information

Product Name	1,2-Cyclohexanedicarboxylic Acid, 4-Oxo-, 1,2-Dimethyl Ester, (1R,2R)-Rel-
CAS No.	13991-44-1
Molecular Formula	C10H14O5
Molecular Weight	214.22 g/mol
Synonyms	(1R,2R)-rel-4-Oxo-1,2-cyclohexanedicarboxylic Acid 1,2-Dimethyl Ester; (1R,2R)-rel-1,2-Dimethyl 4-Oxocyclohexane-1,2-dicarboxylate; Dimethyl (1R,2R)-rel-4-Oxocyclohexane-1,2-dicarboxylate; (1R,2R)-rel-4-Oxocyclohexane-1,2-dicarboxylic Acid Dimethyl Ester; 4-Oxo-1,2-cyclohexanedicarboxylic Acid Dimethyl Ester, (1R,2R)-rel-; (rel-(1R,2R))-Dimethyl 4-Oxocyclohexane-1,2-dicarboxylate
EINECS	Contact for details

Quality Control

Our 1,2-Cyclohexanedicarboxylic Acid, 4-Oxo-, 1,2-Dimethyl Ester, (1R,2R)-Rel- is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques. We support cGMP manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	≥ 99.0% de (for (1R,2R) isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.