Description

3-Azido-3-Deoxy-1,2:5,6-Di-o-Isopropylidene-α-D-Glucofuranose is a key protected carbohydrate intermediate featuring a strategically positioned azido group, which serves as a versatile precursor for further chemical transformations. This compound is critical for the synthesis of modified sugars, nucleosides, and complex bioactive molecules, enabling advanced research and development in medicinal chemistry. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on glycoscience and antiviral/antitumor agent development.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel nucleoside analogs with potential antiviral or anticancer activity.
• Glycochemistry Research: Used in the preparation of azido-sugar derivatives for studying carbohydrate-protein interactions and metabolic pathways.
• Click Chemistry Substrate: The azido functionality allows for efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, facilitating bioconjugation and polymer chemistry.
• Carbohydrate Chemistry: Serves as a protected intermediate for the stereoselective synthesis of deoxyamino sugars and other rare sugar derivatives.
• Probe and Label Development: Utilized in the creation of fluorescent or affinity tags for biological imaging and target identification.

Basic Information

Product Name	3-Azido-3-Deoxy-1,2:5,6-Di-o-Isopropylidene-α-D-Glucofuranose
CAS No.	13964-23-3
Molecular Formula	C12H19N3O5
Molecular Weight	285.30 g/mol
Synonyms	3-Azido-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose; 1,2:5,6-Di-O-isopropylidene-3-azido-3-deoxy-α-D-glucofuranose; 3-Azido-1,2:5,6-di-O-isopropylidene-α-D-allofuranose; 3-Azido-3-deoxy-1,2:5,6-di-O-(1-methylethylidene)-α-D-glucofuranose; 3-Azido-di-O-isopropylidene-glucofuranose; Protected 3-azido glucofuranose
EINECS	Contact for details

Quality Control

Our 3-Azido-3-Deoxy-1,2:5,6-Di-o-Isopropylidene-α-D-Glucofuranose is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and purity. Our quality management system supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and should be handled under an inert atmosphere if prolonged exposure is anticipated to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Specification available upon request
Specific Rotation	Specification available upon request
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.