Description

1-(2-Chloroethyl)-3-Cyclopentyl-1-Nitroso-Urea is a specialized nitrosourea derivative, a class of compounds known for their alkylating properties. This compound is of significant interest in advanced pharmaceutical research and development, particularly in the field of oncology. It serves as a critical intermediate or active pharmaceutical ingredient (API) for researchers and manufacturers developing novel chemotherapeutic agents and targeted therapies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of alkylating antineoplastic agents for cancer treatment research.
• Oncology Research: Used in preclinical and clinical research to study the mechanisms and efficacy of nitrosourea-based chemotherapies.
• Biochemical Research: Employed in laboratory studies to investigate DNA alkylation, cross-linking, and cellular apoptosis pathways.
• API Synthesis: Serves as a precursor in the controlled synthesis of complex active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Academic & Institutional Research: Utilized by universities and research institutes for chemical biology and medicinal chemistry programs.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	1-(2-Chloroethyl)-3-Cyclopentyl-1-Nitroso-Urea
CAS No.	13909-03-0
Molecular Formula	C8H14ClN3O2
Molecular Weight	219.67 g/mol
Synonyms	1-(2-Chloroethyl)-3-cyclopentyl-1-nitrosourea; CCNU (Lomustine) related analog; N-(2-Chloroethyl)-N'-cyclopentyl-N-nitrosourea; 1-Nitroso-1-(2-chloroethyl)-3-cyclopentylurea; Cyclopentyl CCNU derivative; Chloroethyl Cyclopentyl Nitrosourea; Nitrosourea derivative (chloroethyl cyclopentyl); UNII-Contact for details
EINECS	Contact for details

Quality Control

Our 1-(2-Chloroethyl)-3-Cyclopentyl-1-Nitroso-Urea is manufactured and handled under strict quality systems to ensure batch-to-batch consistency and reliability for research applications. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by HPLC, NMR, and IR spectroscopy. Quality is assured in alignment with ICH guidelines for impurities, and custom synthesis can be performed to meet specific pharmacopeial or internal standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) or as specified on the label. Due to its sensitivity to light and oxidation, prolonged exposure to air and light should be avoided. Keep the container in a cool, dry, well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.