Description

1-(2-Chloroethyl)-3-(2,6-Dioxo-3-Piperidyl)-1-Nitrosourea is a specialized nitrosourea derivative of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key synthetic intermediate in the creation of novel therapeutic agents, particularly in oncology. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of experimental anti-cancer agents and other bioactive compounds.
• Oncology Research: Used in academic and industrial laboratories to develop and study new nitrosourea-based chemotherapeutic candidates.
• Medicinal Chemistry: Serves as a precursor for structure-activity relationship (SAR) studies and lead optimization processes.
• Bioconjugation Studies: Potential use in developing targeted drug delivery systems due to its reactive functional groups.
• Process Chemistry: Employed in scale-up and route development for the manufacture of active pharmaceutical ingredients (APIs).
• Biochemical Tool Compound: Used in mechanistic studies to understand alkylating agent activity and DNA interaction.

Basic Information

Product Name	1-(2-Chloroethyl)-3-(2,6-Dioxo-3-Piperidyl)-1-Nitrosourea
CAS No.	13909-02-9
Molecular Formula	C8H11ClN4O4
Molecular Weight	262.65 g/mol
Synonyms	1-(2-Chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea; 3-[3-(2-Chloroethyl)-3-nitrosoureido]piperidine-2,6-dione; Nitrosourea, 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl)-; CENU (common abbreviation for chloroethyl nitrosoureas); 13909-02-9; 1-Nitrosourea, 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl)-; 3-(3-(2-Chloroethyl)-3-nitrosoureido)-2,6-piperidinedione
EINECS	Contact for details

Quality Control

Our 1-(2-Chloroethyl)-3-(2,6-Dioxo-3-Piperidyl)-1-Nitrosourea is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for demanding research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research-grade chemicals, and custom synthesis and purification to specific customer specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) or as specified on the label. This compound is strictly light-sensitive and easily oxidized; prolonged exposure to light, air, or moisture must be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.