Description

1-(2-Chloroethyl)-3-(2-Fluoroethyl)-1-Nitrosourea is a specialized alkylating nitrosourea derivative of significant interest in advanced chemical research and development. This compound matters for its role as a key synthetic intermediate and a model compound for studying the structure-activity relationships of biologically active nitrosoureas. It is primarily needed by researchers and development teams in the pharmaceutical, agrochemical, and specialty chemical industries, particularly those focused on oncology research and novel therapeutic agent synthesis.

Application

• Pharmaceutical Research Intermediate: Serves as a critical building block in the synthesis of novel chemotherapeutic agents and targeted cancer therapies.
• Biochemical Probe Development: Used in academic and industrial laboratories to study alkylation mechanisms, DNA cross-linking, and the biological effects of nitrosourea compounds.
• Agrochemical Synthesis: Acts as a precursor in the development of new active ingredients with herbicidal or pesticidal properties.
• Process Chemistry & Scale-Up: Employed in process optimization and route scouting for the commercial production of complex molecules.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.
• Material Science Research: Investigated for potential applications in creating functional polymers or advanced materials with specific reactivity.

Basic Information

Product Name	1-(2-Chloroethyl)-3-(2-Fluoroethyl)-1-Nitrosourea
CAS No.	13907-77-2
Molecular Formula	C5H9ClFN3O2
Molecular Weight	197.59 g/mol
Synonyms	1-(2-Chloroethyl)-3-(2-fluoroethyl)-1-nitrosourea; N-(2-Chloroethyl)-N'-nitroso-N-(2-fluoroethyl)urea; 1-Nitrosourea, 1-(2-chloroethyl)-3-(2-fluoroethyl)-; CENU (Fluoro-chloro analog); FCNU; 1-(2-Fluoroethyl)-3-(2-chloroethyl)-1-nitrosourea (isomer); Nitrosourea FCE; Urea, N-(2-chloroethyl)-N'-nitroso-N-(2-fluoroethyl)-
EINECS	Contact for details

Quality Control

Our 1-(2-Chloroethyl)-3-(2-Fluoroethyl)-1-Nitrosourea is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), related substances, and identification (IR/NMR). Our quality commitment aligns with cGMP principles for research materials, ensuring reliable and reproducible performance for your critical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C (refrigerated) under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation and decomposition. The container should be kept in a cool, dry, well-ventilated place separate from incompatible materials. Allow the container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.