Description

1,1'-(1α,4β-Cyclohexylene)Bis[3-(2-Chloroethyl)-3-Nitrosourea] is a specialized bifunctional alkylating agent belonging to the nitrosourea class of compounds. This high-purity intermediate is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel chemotherapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on oncology and targeted drug discovery.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of experimental chemotherapeutic drugs and targeted cancer therapies.
• Biomedical Research: Used in biochemical studies to investigate DNA alkylation mechanisms and cell cycle inhibition.
• Antineoplastic Agent Development: Serves as a core structural component for developing new nitrosourea-based anticancer compounds.
• Preclinical Studies: Employed in laboratory-scale formulation and efficacy testing of potential oncology candidates.
• Chemical Biology Probes: Utilized to create tools for studying enzyme interactions and cellular signaling pathways affected by alkylation.

Basic Information

Product Name	1,1'-(1α,4β-Cyclohexylene)Bis[3-(2-Chloroethyl)-3-Nitrosourea]
CAS No.	13907-57-8
Molecular Formula	C14H22Cl2N6O4
Molecular Weight	401.27 g/mol
Synonyms	1,1'-(1,4-Cyclohexylene)bis[3-(2-chloroethyl)-3-nitrosourea]; Cyclohexylidenebis(1-(2-chloroethyl)-1-nitrosourea); BCNU Cyclohexylene Derivative; 1,4-Cyclohexylene Bis(Chloroethyl Nitrosourea); NSC 82196; Nitrosourea Bifunctional Alkylating Agent; 1,1'-(1,4-Cyclohexanediyl)bis[3-(2-chloroethyl)-3-nitrosourea]
EINECS	Contact for details

Quality Control

Our 1,1'-(1α,4β-Cyclohexylene)Bis[3-(2-Chloroethyl)-3-Nitrosourea] is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.