Description

(8α)-3-Methoxy-1,3,5(10)-Estratrien-17-One CAS NO 13865-88-8 is a high-purity steroid derivative and a key synthetic intermediate in advanced pharmaceutical research and development. This compound is valued for its precise chemical structure, which serves as a critical building block in the synthesis of complex therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on developing novel steroid-based treatments and conducting detailed metabolic studies.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for hormonal therapies.
• Research & Development: Used in academic and industrial laboratories for investigating steroid metabolism, receptor binding, and structure-activity relationships (SAR).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis using HPLC, GC, or LC-MS.
• Process Chemistry: Employed in scaling up synthetic routes during process development and optimization for new drug candidates.
• Biochemical Studies: Utilized in enzymatic studies and metabolic pathway research related to steroid hormones.

Basic Information

Product Name	(8α)-3-Methoxy-1,3,5(10)-Estratrien-17-One
CAS No.	13865-88-8
Molecular Formula	C19H24O2
Molecular Weight	284.39 g/mol
Synonyms	8α-Estrone 3-methyl ether; 8α-Estrone methyl ether; 3-Methoxy-8α-estra-1,3,5(10)-trien-17-one; 8α-Hydroxyestrone 3-methyl ether (keto form); 17-Oxo-8α-estra-1,3,5(10)-trien-3-ol methyl ether
EINECS	Contact for details

Quality Control

Our (8α)-3-Methoxy-1,3,5(10)-Estratrien-17-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by chromatographic techniques, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.