Description

Ethyl 2-Isocyanatopropionate is a versatile isocyanate ester monomer used in the synthesis of specialized polymers and fine chemicals. This compound is valued for its reactive isocyanate group, which enables the formation of urethane, urea, and other functional linkages under mild conditions. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and prodrugs, particularly those requiring carbamate or urea functional groups.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where it introduces the isocyanate moiety for enhanced biological activity.
• Polymer Modification: Serves as a reactive monomer or cross-linking agent in polyurethane and polyurea systems to tailor flexibility, adhesion, and chemical resistance.
• Specialty Coatings & Adhesives: Imparts durability and specific reactivity in high-performance coating formulations and adhesive systems.
• Chemical Research (R&D): Employed in academic and industrial laboratories for developing novel heterocyclic compounds, peptides, and functional materials.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex organic molecules for electronics, dyes, and flavors/fragrances.

Basic Information

Product Name	Ethyl 2-Isocyanatopropionate
CAS No.	13794-28-0
Molecular Formula	C6H9NO3
Molecular Weight	143.14 g/mol
Synonyms	Ethyl 2-isocyanatopropanoate; 2-Isocyanatopropionic Acid Ethyl Ester; Propanoic acid, 2-isocyanato-, ethyl ester; Ethyl α-isocyanatopropionate; NSC 163045; Ethyl 2-(isocyanato)propanoate; Ethyl ester of 2-isocyanatopropionic acid
EINECS	Contact for details

Quality Control

Our Ethyl 2-Isocyanatopropionate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay by GC/HPLC, identity confirmation (IR, NMR), and impurity profiling, to ensure high purity and consistency. Certificates of Analysis (COA) documenting all specifications are provided with every shipment. We adhere to cGMP standards where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at temperatures between 2°C and 8°C (refrigerated) or as specified on the label. Due to its highly volatile and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent polymerization or hydrolysis. Keep away from heat, sparks, open flames, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	~1.08 g/cm³
Refractive Index (n20D)	~1.420 - 1.425

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.