Description

tert-Butyl L-Lactate is a high-purity chiral ester derived from L-lactic acid, serving as a critical chiral building block and protecting group reagent in advanced organic synthesis. Its value lies in providing a sterically hindered, acid-labile protecting group for carboxylic acids, enabling selective reactions in complex molecule assembly. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients and fine chemicals with specific stereochemical requirements.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic disorders.
• Carboxyl Group Protection: Used as a protecting group reagent in peptide synthesis and complex natural product synthesis, where its tert-butyl ester can be selectively cleaved under mild acidic conditions.
• Agrochemical Synthesis: Employed in the production of chiral herbicides, fungicides, and plant growth regulators where biological activity is stereospecific.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as in hydrogenation or cross-coupling reactions.
• Flavor and Fragrance Industry: Utilized in the synthesis of chiral esters and lactones that contribute to specific flavor profiles and aromatic compounds.
• Polymer Modification: Acts as a monomer or modifying agent for creating polymers with tailored degradation profiles or specific tacticity.

Basic Information

Item	Details
Product Name	tert-Butyl L-Lactate
CAS No.	13650-70-9
Molecular Formula	C7H14O3
Molecular Weight	146.18 g/mol
Synonyms	(S)-2-Hydroxypropanoic acid 1,1-dimethylethyl ester; L-(-)-Lactic acid tert-butyl ester; (S)-tert-Butyl lactate; tert-Butyl (S)-lactate; (S)-2-Hydroxypropionic acid tert-butyl ester; L-Lactic acid tert-butyl ester; tert-Butyl (S)-2-hydroxypropanoate
EINECS	Contact for details

Quality Control

Our tert-Butyl L-Lactate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, identity confirmation by IR and NMR spectroscopy, and determination of chemical purity. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.