Description

2,6-Diazaspiro[3.3]Heptane, 2,6-Bis[(4-Methylphenyl)Sulfonyl]- is a high-value, synthetically versatile spirocyclic building block featuring a rigid diazaspiro[3.3]heptane core protected by tosyl groups. This compound matters as a critical intermediate in modern pharmaceutical and agrochemical research, enabling the construction of complex three-dimensional molecular architectures essential for developing new active ingredients. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and crop protection industries for applications in drug discovery and advanced material synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key scaffold in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets and enzyme inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific three-dimensional shape for target binding.
• Ligand Synthesis: Acts as a precursor for constructing sophisticated chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed to create tool compounds and probes for studying biological pathways and protein function.
• Peptidomimetics: The spirocyclic structure is valuable for designing conformationally restricted peptide analogs with enhanced stability and bioavailability.
• Material Science: Potential building block for advanced polymers and functional materials with unique thermal or mechanical properties.

Basic Information

Item	Details
Product Name	2,6-Diazaspiro[3.3]Heptane, 2,6-Bis[(4-Methylphenyl)Sulfonyl]-
CAS No.	13595-48-7
Molecular Formula	C19H22N2O4S2
Molecular Weight	406.52 g/mol
Synonyms	2,6-Bis(p-toluenesulfonyl)-2,6-diazaspiro[3.3]heptane; 2,6-Ditosyl-2,6-diazaspiro[3.3]heptane; 2,6-Diazaspiro[3.3]heptane-2,6-diyl bis(4-methylbenzenesulfonate); N,N'-Ditosyl-2,6-diazaspiro[3.3]heptane; Spirocyclic Tosyl-protected Diamine; 13595-48-7; 2,6-Diazaspiro[3.3]heptane bis(tosylate) derivative
EINECS	Contact for details

Quality Control

Our 2,6-Diazaspiro[3.3]Heptane, 2,6-Bis[(4-Methylphenyl)Sulfonyl]- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with full analytical data are provided to guarantee traceability and consistency for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.