Description

(2S)-1-Triphenylmethyl-2-Pyrrolidinecarboxylic Acid Methyl Ester is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for constructing complex molecules with defined stereochemistry, which is critical for efficacy in many applications. This compound is essential for research and production in the pharmaceutical industry, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the asymmetric synthesis of various drug candidates and active pharmaceutical ingredients (APIs).
• Catalyst and Ligand Synthesis: Used as a precursor for the preparation of specialized ligands and organocatalysts in asymmetric catalysis.
• Peptidomimetic Research: Serves as a proline derivative building block for the design and synthesis of peptidomimetics and constrained peptides.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals requiring precise stereocontrol.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research laboratories.

Basic Information

Product Name	(2S)-1-Triphenylmethyl-2-Pyrrolidinecarboxylic Acid Methyl Ester
CAS No.	13515-74-7
Molecular Formula	C25H25NO2
Molecular Weight	371.47 g/mol
Synonyms	L-Proline, 1-(triphenylmethyl)-, methyl ester; Methyl (2S)-1-trityl-2-pyrrolidinecarboxylate; (S)-1-Trityl-2-pyrrolidinecarboxylic acid methyl ester; Methyl 1-trityl-L-prolinate; Methyl 1-trityl-(S)-prolinate; 1-Trityl-L-proline methyl ester; (S)-1-Tritylpyrrolidine-2-carboxylic acid methyl ester; L-Proline methyl ester, N-trityl-
EINECS	Contact for details

Quality Control

Our (2S)-1-Triphenylmethyl-2-Pyrrolidinecarboxylic Acid Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We employ advanced analytical techniques, including HPLC, GC, and chiral analysis, to verify identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.