Description

2,3,4,5-Tetra-o-Acetyl-D-Xylonitrile is a key protected sugar intermediate, specifically a fully acetylated nitrile derivative of D-xylose. This compound is of significant value in synthetic organic chemistry for the controlled construction of complex carbohydrate and nucleoside analogs. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral agents, nucleotide-based therapeutics, and novel chiral building blocks.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of nucleoside analogs and antiviral drugs.
• Carbohydrate Chemistry Research: Serves as a protected starting material for the synthesis of modified sugars and glycomimetics.
• Chiral Pool Synthesis: Provides a source of chirality for the asymmetric synthesis of complex natural products and active pharmaceutical ingredients (APIs).
• Nucleotide Chemistry: Used in the preparation of modified nucleosides and nucleotides for biochemical and therapeutic applications.
• Glycoconjugate Development: Acts as a building block for creating glycoconjugates with potential diagnostic or therapeutic uses.
• Process Chemistry & Scale-up: Employed in route development and optimization for the commercial production of carbohydrate-based molecules.

Basic Information

Product Name	2,3,4,5-Tetra-o-Acetyl-D-Xylonitrile
CAS No.	13501-95-6
Molecular Formula	C13H15NO8
Molecular Weight	313.26 g/mol
Synonyms	D-Xylonitrile, 2,3,4,5-tetraacetate; 2,3,4,5-Tetra-O-acetyl-D-xylononitrile; (2R,3S,4R)-2,3,4-Triacetoxy-5-cyano-5-(acetoxymethyl)tetrahydrofuran; Tetra-O-acetyl-D-xylonitrile; D-Xylose tetraacetate cyanohydrin; Acetylated D-xylonitrile
EINECS	Contact for details

Quality Control

Our 2,3,4,5-Tetra-o-Acetyl-D-Xylonitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.