Description

n-[n-Acetyl-4-[Bis(2-Chloroethyl)Amino]Phenylalanyl]Valine Ethyl Ester is a specialized synthetic peptide derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block or intermediate in the synthesis of more complex therapeutic agents, particularly those targeting specific cellular pathways. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing novel drug candidates, especially in oncology and targeted therapy domains.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of peptide-based drug candidates and targeted chemotherapeutic agents.
• Oncology Research: Used in the development and study of novel compounds designed for targeted cancer therapy due to its structural motifs.
• Bioconjugation Studies: Serves as a model compound or reagent in studies involving the conjugation of peptides to other molecules or delivery systems.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for producing high-value, complex molecular entities.
• Biochemical Research: Used as a tool compound to investigate enzyme interactions or specific biological pathways in a laboratory setting.

Basic Information

Product Name	n-[n-Acetyl-4-[Bis(2-Chloroethyl)Amino]Phenylalanyl]Valine Ethyl Ester
CAS No.	13425-94-0
Molecular Formula	C24H36Cl2N4O5
Molecular Weight	531.47 g/mol
Synonyms	N-Acetylmelphalan-phe-val-OEt; L-Phenylalanine, N-acetyl-4-[bis(2-chloroethyl)amino]-, 1-(1-ethoxycarbonyl-2-methylpropyl) ester; Acetylmelphalan phenylalanylvaline ethyl ester; N-AC-MEL-PHE-VAL-OET; 4-[Bis(2-chloroethyl)amino]-N-acetyl-L-phenylalanyl-L-valine ethyl ester; N-α-Acetyl-4-[bis(2-chloroethyl)amino]-L-phenylalanyl-L-valine ethyl ester; Melphalan derivative peptide ester
EINECS	Contact for details

Quality Control

Our n-[n-Acetyl-4-[Bis(2-Chloroethyl)Amino]Phenylalanyl]Valine Ethyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral purity analysis, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep container tightly sealed in a dry and well-ventilated place. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.