Description

2',4-Dihydroxy-4'-Methoxychalcone is a naturally occurring chalcone derivative, a class of compounds known for their significant biological and chemical properties. This compound matters as a versatile intermediate and active ingredient, offering a unique structural scaffold for research and development. It is primarily needed by the pharmaceutical, nutraceutical, and cosmetic industries for applications in drug discovery, functional ingredient formulation, and as a reference standard for analytical purposes.

Application

• Pharmaceutical Research & Development: As a key intermediate or lead compound in the synthesis of novel therapeutic agents, particularly for anti-inflammatory, antioxidant, and anticancer studies.
• Nutraceutical & Dietary Supplements: Utilized as a bioactive ingredient or a marker compound in formulations targeting oxidative stress and metabolic health.
• Cosmetic & Personal Care: Incorporated into skincare products for its potential antioxidant and skin-brightening properties.
• Analytical & Reference Standards: Serves as a high-purity certified reference material (CRM) for quality control, method validation, and regulatory compliance in analytical laboratories.
• Chemical Synthesis: Acts as a fundamental building block for the preparation of more complex flavonoids and heterocyclic compounds in organic chemistry.
• Academic & Institutional Research: Used in biochemical, pharmacological, and phytochemical studies to investigate structure-activity relationships and biological pathways.

Basic Information

Product Name	2',4-Dihydroxy-4'-Methoxychalcone
CAS No.	13351-10-5
Molecular Formula	C₁₆H₁₄O₄
Molecular Weight	270.28 g/mol
Synonyms	4'-Methoxy-2,4-dihydroxychalcone; (E)-1-(2,4-Dihydroxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one; 2',4-Dihydroxy-4'-methoxy-trans-chalcone; 4-Methoxy-2',4'-dihydroxychalcone; Chalcone, 2',4-dihydroxy-4'-methoxy-; NSC 407303; Butein 4'-methyl ether
EINECS	Contact for details

Quality Control

Our 2',4-Dihydroxy-4'-Methoxychalcone is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment supports applications requiring research, development, and cGMP-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Melting Point	185 - 195 °C
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.