Description

1-(2,2,2-Trifluoroethyl)Piperazine is a versatile fluorinated piperazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of a reactive piperazine ring with a stable trifluoroethyl group, enabling the introduction of fluorine atoms to modulate the properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) drugs and other bioactive molecules where fluorine substitution is desired.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the trifluoroethyl group to enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands in coordination chemistry and catalysts for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced materials with specific thermal or surface properties.
• Custom Synthesis and R&D: A valuable scaffold for medicinal chemistry and process research in contract research and manufacturing organizations (CROs/CMOs).

Basic Information

Product Name	1-(2,2,2-Trifluoroethyl)Piperazine
CAS No.	13349-90-1
Molecular Formula	C6H11F3N2
Molecular Weight	168.16 g/mol
Synonyms	1-(2,2,2-Trifluoroethyl)piperazine; N-(2,2,2-Trifluoroethyl)piperazine; 2,2,2-Trifluoroethylpiperazine; 1-Trifluoroethylpiperazine; Piperazine, 1-(2,2,2-trifluoroethyl)-; 13349-90-1; N-Trifluoroethylpiperazine; Trifluoroethylpiperazine
EINECS	Contact for details

Quality Control

Our 1-(2,2,2-Trifluoroethyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay by HPLC, identification by FT-IR, and impurity profiling, to ensure it meets the high-purity standards required for research and industrial synthesis. Certificates of Analysis (COA) are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong acids and oxidizing agents. Due to its basic nature, handle with appropriate personal protective equipment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.