Description

1-(Trimethylsilyl)Ethanol, 98 is a versatile organosilicon compound featuring both a reactive hydroxyl group and a hydrolytically stable trimethylsilyl protecting group. This dual functionality makes it a valuable intermediate and protecting agent in sophisticated organic synthesis, particularly for the pharmaceutical and agrochemical sectors. It is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), specialty polymers, and advanced materials where precise control over molecular architecture is required. The high purity grade (98%) ensures consistent performance and reliability in critical synthetic pathways.

Application

• Pharmaceutical Intermediate: Used in the synthesis of complex drug molecules, serving as a protected alcohol synthon or a precursor for silicon-containing bioactive compounds.
• Agrochemical Synthesis: Acts as a key building block in the production of advanced pesticides and herbicides that require silicon-enhanced stability or bioavailability.
• Polymer & Material Science: Employed as a monomer or modifying agent in the creation of specialty silicones, coatings, and adhesives with tailored surface properties.
• Organic Synthesis Reagent: Functions as a versatile reagent for introducing the trimethylsilylethanol moiety, which can act as a protecting group for alcohols in multi-step syntheses.
• Cross-coupling Reactions: Serves as a substrate in palladium-catalyzed and other metal-mediated coupling reactions to construct complex molecular frameworks.
• Surface Modification: Used to derivatize silica gels, glass, or other oxides to create hydrophobic surfaces for chromatography or material science applications.

Basic Information

Product Name	1-(Trimethylsilyl)Ethanol, 98
CAS No.	13246-39-4
Molecular Formula	C5H14OSi
Molecular Weight	118.25 g/mol
Synonyms	2-(Trimethylsilyl)ethanol; β-(Trimethylsilyl)ethanol; Trimethylsilylethanol; Hydroxyethyltrimethylsilane; (2-Hydroxyethyl)trimethylsilane; TMS-Ethanol; 2-(Trimethylsilyl)ethan-1-ol; NSC 163082
EINECS	236-235-8

Quality Control

Our 1-(Trimethylsilyl)Ethanol, 98 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure it meets the declared purity and specification. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance for your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.