Description

Rs-4-Methoxyphenylglycine Methyl Ester Hydrochloride is a key chiral building block and intermediate in organic synthesis. This high-purity compound is critical for ensuring the stereochemical integrity and yield of downstream pharmaceutical products. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development and production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the synthesis of complex drug molecules, particularly those requiring specific enantiomeric purity.
• Peptide Synthesis: Used as a protected amino acid derivative in the preparation of modified peptides and peptidomimetics.
• Agrochemical Research: Serves as a building block for developing novel, optically active agrochemicals and herbicides.
• Asymmetric Catalysis: Employed as a ligand precursor or a substrate in catalytic asymmetric transformations.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Fine Chemical Production: Used in the custom synthesis of specialty chemicals and advanced materials.

Basic Information

Product Name	Rs-4-Methoxyphenylglycine Methyl Ester Hydrochloride
CAS No.	13226-99-8
Molecular Formula	C10H14ClNO3
Molecular Weight	231.68 g/mol
Synonyms	(R)-2-Amino-2-(4-methoxyphenyl)acetic acid methyl ester hydrochloride; Methyl (R)-2-amino-2-(4-methoxyphenyl)acetate hydrochloride; (R)-4-Methoxyphenylglycine methyl ester HCl; D-4-Methoxyphenylglycine methyl ester hydrochloride; (R)-α-Amino-4-methoxybenzeneacetic acid methyl ester hydrochloride; Methyl (R)-α-amino-4-methoxybenzeneacetate hydrochloride; (R)-Methyl 2-amino-2-(4-methoxyphenyl)acetate hydrochloride
EINECS	Contact for details

Quality Control

Our Rs-4-Methoxyphenylglycine Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (HPLC) and chemical identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen atmosphere) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.