Description

2,3,4,6-Tetra-o-Benzyl-D-Glucono-1,5-Lactone is a key protected sugar derivative and versatile chiral building block in advanced organic synthesis. Its value lies in providing a selectively benzylated glucose scaffold, enabling the controlled introduction of glycosidic linkages and complex carbohydrate structures. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for synthesizing nucleoside analogs, antiviral agents, and complex oligosaccharides.

Application

• Pharmaceutical Intermediate: Critical starting material for the synthesis of novel nucleoside-based drugs and antiviral compounds.
• Glycosylation Reagent: Used in the stereoselective construction of glycosidic bonds for complex carbohydrate and glycoconjugate synthesis.
• Chiral Pool Synthesis: Serves as a readily available chiral template for the preparation of enantiomerically pure natural products and bioactive molecules.
• Carbohydrate Chemistry Research: A fundamental reagent for studying glycosylation mechanisms and developing new synthetic methodologies.
• Oligosaccharide Assembly: Building block for the stepwise, controlled synthesis of defined oligosaccharides and glycodendrimers.
• Protecting Group Strategy: The benzyl groups provide orthogonal protection, allowing for sequential deprotection in multi-step synthetic sequences.

Basic Information

Product Name	2,3,4,6-Tetra-o-Benzyl-D-Glucono-1,5-Lactone
CAS No.	13096-62-3
Molecular Formula	C34H34O6
Molecular Weight	538.63 g/mol
Synonyms	2,3,4,6-Tetra-O-benzyl-D-glucono-1,5-lactone; Tetra-O-benzyl-D-gluconolactone; D-Glucono-1,5-lactone, 2,3,4,6-tetra-O-benzyl-; 2,3,4,6-Tetra-O-benzylglucono-1,5-lactone; 2,3,4,6-Tetra-O-benzyllactone; 13096-62-3; Gluconolactone, tetra-O-benzyl-
EINECS	Contact for details

Quality Control

Our 2,3,4,6-Tetra-o-Benzyl-D-Glucono-1,5-Lactone is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical starting materials, ensuring traceability and documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.