Description

β-D-Ribofuranose 1,2,3,5-Tetraacetate is a key acetylated ribose derivative, serving as a vital protected intermediate in organic synthesis. Its primary value lies in providing a stable, reactive scaffold for the controlled construction of nucleosides, nucleotides, and complex carbohydrate molecules. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, where precise molecular assembly is critical.

Application

• Nucleoside/Nucleotide Synthesis: A fundamental protected intermediate for the production of modified nucleosides, antiviral agents, and mRNA vaccine components.
• Carbohydrate Chemistry: Used as a chiral starting material or building block for the synthesis of complex oligosaccharides, glycoconjugates, and glycomimetics.
• Pharmaceutical Intermediates: Serves in the research and development of active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer drug candidates.
• Biochemical Research: Employed in enzymatic studies, metabolic pathway analysis, and as a precursor for labeled compounds in tracer studies.
• Fine Chemical Production: Acts as a specialty intermediate for catalysts, ligands, and other high-value chemical entities requiring a ribose backbone.

Basic Information

Product Name	β-D-Ribofuranose 1,2,3,5-Tetraacetate
CAS No.	13035-61-5
Molecular Formula	C13H18O9
Molecular Weight	318.28 g/mol
Synonyms	1,2,3,5-Tetra-O-acetyl-β-D-ribofuranose; β-D-Ribofuranose 1,2,3,5-tetraacetate; Tetra-O-acetyl-β-D-ribofuranose; 1,2,3,5-Tetra-O-acetyl-D-ribofuranose; Acetylated D-ribose; D-Ribose tetraacetate; β-D-Ribofuranose tetraacetate; 2,3,5-Tri-O-acetyl-1-O-acetyl-β-D-ribofuranose
EINECS	235-891-1

Quality Control

Our β-D-Ribofuranose 1,2,3,5-Tetraacetate is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and optical rotation, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	-18.0° to -22.0° (c=1 in CHCl₃)
Melting Point	88°C - 92°C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.