Description

Ethyl (R)-(-)-Mandelate is a high-purity chiral ester of mandelic acid, serving as a critical chiral building block and resolving agent in asymmetric synthesis. Its value lies in providing a defined stereochemical center for the production of enantiomerically pure pharmaceuticals and fine chemicals. This product is essential for R&D and manufacturing chemists in the pharmaceutical, agrochemical, and advanced material sectors who require high optical purity intermediates.

Application

• Chiral Intermediate in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Resolving Agent for the separation of racemic mixtures of amines and other basic compounds.
• Building Block for the preparation of chiral ligands and catalysts used in asymmetric catalysis.
• Precursor in the development of specialty chemicals and flavor/fragrance compounds with specific stereochemistry.
• Reference Standard for analytical method development and quality control in chiral HPLC analysis.

Basic Information

Product Name	Ethyl (R)-(-)-Mandelate
CAS No.	10606-72-1
Molecular Formula	C10H12O3
Molecular Weight	180.20 g/mol
Synonyms	(R)-(-)-Ethyl Mandelate; (R)-Ethyl 2-Hydroxy-2-phenylacetate; (-)-Ethyl Mandelate; D-(-)-Ethyl Mandelate; Ethyl (R)-2-Hydroxy-2-phenylacetate; Ethyl (R)-α-Hydroxybenzeneacetate; (R)-Mandelic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl (R)-(-)-Mandelate is manufactured under a strict quality management system. Each batch is tested to ensure high chemical and optical purity, with specifications typically covering appearance, assay, enantiomeric excess (e.e.), and specific rotation. Certificates of Analysis (COA) documenting all test results are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product is moisture-sensitive (hygroscopic); keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (e.e.)	≥ 99.0%
Specific Rotation [α]20/D	-40° to -44° (c=1 in ethanol)
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.