Description

3-Ethynyl-Benzoic Acid Methyl Ester is a versatile aromatic alkyne derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an ethynyl group and a methyl ester, makes it a valuable precursor for constructing complex molecular architectures through cross-coupling and cycloaddition reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, dendrimers, and conductive materials.
• Organic Ligand Precursor: Employed in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D for exploring new synthetic methodologies, including Sonogashira and Click chemistry.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex dyes, flavors, and fragrances.

Basic Information

Product Name	3-Ethynyl-Benzoic Acid Methyl Ester
CAS No.	10602-06-9
Molecular Formula	C10H8O2
Molecular Weight	160.17 g/mol
Synonyms	Methyl 3-Ethynylbenzoate; 3-Ethynyl Methyl Benzoate; Benzoic acid, 3-ethynyl-, methyl ester; Methyl m-Ethynylbenzoate; 3-Carbomethoxyphenylacetylene; m-(Methoxycarbonyl)phenylacetylene
EINECS	Contact for details

Quality Control

Our 3-Ethynyl-Benzoic Acid Methyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation by FT-IR and NMR, and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.