Description

2-O,3-O,5-o-Tris(Trimethylsilyl)-D-Xylonic Acid γ-Lactone is a key protected sugar derivative and versatile synthetic intermediate in advanced organic chemistry. Its primary value lies in enabling the selective manipulation of carbohydrate hydroxyl groups, which is critical for the synthesis of complex, biologically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity building blocks for nucleoside, carbohydrate, and natural product synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Carbohydrate Chemistry: Used for the selective protection and functionalization of sugar molecules in the development of complex oligosaccharides and glycoconjugates.
• Chiral Synthesis: Acts as a valuable chiral pool starting material or auxiliary for the asymmetric synthesis of natural products and specialty chemicals.
• Agrochemical Research: Employed in the development of novel, bioactive compounds with specific stereochemical configurations for crop protection.
• Fine Chemical Production: Utilized in custom synthesis and process development for high-value, low-volume specialty chemicals.
• Academic & R&D: A fundamental reagent in university and corporate research laboratories exploring new synthetic methodologies and molecular design.

Basic Information

Product Name	2-O,3-O,5-o-Tris(Trimethylsilyl)-D-Xylonic Acid γ-Lactone
CAS No.	10589-36-3
Molecular Formula	C14H32O5Si3
Molecular Weight	364.66 g/mol
Synonyms	D-Xylonic acid, 2,3,5-tris-O-(trimethylsilyl)-, γ-lactone; 2,3,5-Tri-O-trimethylsilyl-D-xylono-1,4-lactone; Tris(trimethylsilyl) D-xylonolactone; TMS-protected D-xylonolactone; 1,4-Anhydro-2,3,5-tri-O-trimethylsilyl-D-xylitol; (3R,4R,5R)-3,4-Bis(trimethylsilyloxy)-5-[(trimethylsilyloxy)methyl]dihydrofuran-2(3H)-one
EINECS	Contact for details

Quality Control

Every batch of 2-O,3-O,5-o-Tris(Trimethylsilyl)-D-Xylonic Acid γ-Lactone undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC/NMR), identity confirmation, and impurity profile is provided with each shipment to guarantee material integrity for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.