Description

[R,(-)]-1-O,2-o-Distearoyl-3-o-Trityl-D-Glycerol is a high-purity, chiral glycerol derivative, specifically protected at the sn-3 position with a trityl group and esterified at the sn-1 and sn-2 positions with stearic acid. This compound matters as a critical chiral building block and intermediate in sophisticated organic synthesis, offering precise stereochemical control for researchers and manufacturers. It is primarily needed by the pharmaceutical, agrochemical, and advanced materials industries for the development of enantiomerically pure drugs, specialty chemicals, and novel lipid-based systems.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly in lipid-based drug formulations and prodrugs.
• Lipid Research & Development: Serves as a protected precursor in the study and synthesis of complex, structured phospholipids and glycolipids for biomedical applications.
• Asymmetric Catalyst Ligand Synthesis: Used to construct chiral ligands and auxiliaries for catalytic processes requiring high enantioselectivity.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and verification of related compounds.
• Advanced Material Synthesis: A building block for creating functionalized polymers and surfactants with specific stereochemical properties.
• Agrochemical Synthesis: Intermediate in the production of enantiomerically pure pesticides and plant growth regulators.

Basic Information

Product Name	[R,(-)]-1-O,2-o-Distearoyl-3-o-Trityl-D-Glycerol
CAS No.	10567-48-3
Molecular Formula	C72H112O5
Molecular Weight	1057.66 g/mol
Synonyms	(R)-1,2-Distearoyl-3-trityl-sn-glycerol; 1,2-Di-O-stearoyl-3-O-trityl-sn-glycerol; sn-Glycerol 1,2-distearate 3-trityl ether (R)-; D-α,β-Distearin 3-trityl ether; 3-O-Trityl-1,2-di-O-stearoyl-sn-glycerol; Trityl-protected DAG; 1,2-Distearoyl-3-trityl-rac-glycerol (related); Glycerol 1,2-distearate 3-trityl ether
EINECS	Contact for details

Quality Control

Our [R,(-)]-1-O,2-o-Distearoyl-3-o-Trityl-D-Glycerol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.