Description

(2S,3S,4S,6'Aα)-6'α-(β-D-Glucopyranosyloxy)-3,4,3'A,5',6',6'A-Hexahydro-3'Aα-Hydroxy-3,4-Dimethylspiro[Furan-2(5H),3'(2'H)-Furo[3,2-B]Furan]-2',5-Dione is a complex, high-purity spirocyclic furanone derivative with a glycosylated structure. This compound is valued for its unique stereochemistry and functional groups, making it a critical advanced intermediate in sophisticated organic syntheses. It is primarily sought by research institutions and pharmaceutical developers for drug discovery programs and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of potential active pharmaceutical ingredients (APIs), particularly in oncology and metabolic disease research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis due to its complex, multi-functional scaffold.
• Glycoscience Studies: Acts as a specialized substrate or probe in enzymatic and chemical glycosylation research.
• Natural Product Synthesis: Employed in the total or semi-synthesis of complex natural products containing spirocyclic or furanone motifs.
• Process Chemistry Development: Used for scaling up synthetic routes and optimizing reaction conditions for pilot-scale production.

Basic Information

Item	Detail
Product Name	(2S,3S,4S,6'Aα)-6'α-(β-D-Glucopyranosyloxy)-3,4,3'A,5',6',6'A-Hexahydro-3'Aα-Hydroxy-3,4-Dimethylspiro[Furan-2(5H),3'(2'H)-Furo[3,2-B]Furan]-2',5-Dione
CAS No.	10563-95-8
Molecular Formula	C18H24O11
Molecular Weight	416.38 g/mol
Synonyms	6'α-(β-D-Glucopyranosyloxy)-3,4,3'A,5',6',6'A-hexahydro-3'Aα-hydroxy-3,4-dimethylspiro[furan-2(5H),3'(2'H)-furo[3,2-b]furan]-2',5-dione; Spiro[furan-2(5H),3'(2'H)-furo[3,2-b]furan]-2',5-dione, 6'α-(β-D-glucopyranosyloxy)-3,4,3'A,5',6',6'A-hexahydro-3'Aα-hydroxy-3,4-dimethyl-, (2S,3S,4S,6'Aα)-; Glucosylspirofuranone derivative; CAS 10563-95-8
EINECS	Contact for details

Quality Control

Our (2S,3S,4S,6'Aα)-6'α-(β-D-Glucopyranosyloxy)-3,4,3'A,5',6',6'A-Hexahydro-3'Aα-Hydroxy-3,4-Dimethylspiro[Furan-2(5H),3'(2'H)-Furo[3,2-B]Furan]-2',5-Dione is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.